A review of exercise pulmonary hypertension in systemic sclerosis
Autor: | Richard N. Channick, Faisal Shaikh, Rajan Saggar, Zafia Anklesaria, Tasneam Shagroni, Michael J. Ryan, Eduardo Bossone, Luna Gargani, Rajeev Saggar |
---|---|
Přispěvatelé: | Shaikh, F, Anklesaria, Z, Shagroni, T, Saggar, R, Gargani, L, Bossone, E, Ryan, M, Channick, R |
Rok vydání: | 2019 |
Předmět: |
medicine.medical_specialty
business.industry Mechanism (biology) Vascular disease Immunology Reviews 030204 cardiovascular system & hematology medicine.disease Pulmonary hypertension Scleroderma 03 medical and health sciences 0302 clinical medicine 030228 respiratory system Rheumatology Internal medicine medicine Cardiology Immunology and Allergy business |
Zdroj: | J Scleroderma Relat Disord |
ISSN: | 2397-1991 2397-1983 |
DOI: | 10.1177/2397198319851653 |
Popis: | In general, pulmonary vascular disease has important negative prognostic implications, regardless of the associated condition or underlying mechanism. In this regard, systemic sclerosis is of particular interest as it is the most common connective tissue disease associated with pulmonary hypertension, and a well-recognized at-risk population. In the setting of systemic sclerosis and unexplained dyspnea, the concept of using exercise to probe for underlying pulmonary vascular disease has acquired significant interest. In theory, a diagnosis of systemic sclerosis–associated exercise pulmonary hypertension may allow for earlier therapeutic intervention and a favorable alteration in the natural history of the pulmonary vascular disease. In the context of underlying systemic sclerosis, the purpose of this article is to provide a comprehensive review of the evolving definition of exercise pulmonary hypertension, the current role and methodologies for non-invasive and invasive exercise testing, and the importance of the right ventricle. |
Databáze: | OpenAIRE |
Externí odkaz: |