Continuous exposure to Kaposi sarcoma-associated herpesvirus (KSHV) in healthcare workers does not result in KSHV infection
| Autor: | Roberta Mancuso, Lucia Brambilla, Ambra Hernis, Athanasia Tourlaki, Mario Clerici, Monica Bellinvia, Simone Agostini, Vinicio Boneschi |
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| Rok vydání: | 2012 |
| Předmět: |
Microbiology (medical)
Adult Male Saliva viruses Health Personnel education Antibodies Viral Seroepidemiologic Studies Occupational Exposure Kaposi sarcoma-associated herpesvirus medicine Humans Continuous exposure biology business.industry virus diseases General Medicine Herpesviridae Infections biochemical phenomena metabolism and nutrition Middle Aged medicine.disease Virology Infectious Diseases Blood Immunology Herpesvirus 8 Human biology.protein Female Sarcoma Occupational exposure Antibody business Horizontal transmission |
| Zdroj: | The Journal of hospital infection. 85(1) |
| ISSN: | 1532-2939 |
| Popis: | Kaposi sarcoma (KS)-associated herpesvirus (KSHV or HHV-8) infection routes and risk of occupational exposure are still ill-defined. We analysed the risk for occupational acquisition of KSHV infection in healthcare workers (HCWs) with prolonged professional exposure to patients with classic KS, comparing the results to those obtained in healthy relatives of KS patients. Serum and/or saliva KSHV-specific antibodies and DNA were detected in five out of 35 healthy relatives of KS patients but in none of the eight HCWs, suggesting that, outside strict family contacts, horizontal transmission of KSHV is highly inefficient even for HCWs with prolonged contact with KS patients. |
| Databáze: | OpenAIRE |
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