Antimicrobial susceptibility assessment of compound from Aspergillus fumigatus

Autor: Sultana Sathi Zakia, Mustafezur Rahman Md., Arifur Rahman Muhammad, AL- Faruk Md., Abdur Rashid Mohammad
Rok vydání: 2015
Předmět:
Zdroj: African Journal of Biotechnology; Vol 14, No 3 (2015); 167-170
ISSN: 1684-5315
DOI: 10.5897/ajb2014.13829
Popis: Ethyl acetate extract of the culture filtrate of Aspergillus fumigatus on chromatographic analysis has led to the isolation of the compound, AF-1 which exhibited a significant in vitro antimicrobial activity against the tested pathogenic microorganism. The structure of the isolated compound, AF-1 was identified as 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one from its IR, UV, EI-MS, 13 C-NMR, 1 H-NMR, HMBC and HMQC data. This is the first report of the compound, AF-1 from the A. fumigatus. Key words: Aspergillus, 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one, antimicrobial screening, bioactive compound.
Databáze: OpenAIRE