Biopsychosocial Rehabilitation for Inflammatory Arthritis and Osteoarthritis Patients: A systematic review and meta-analysis of randomized trials
| Autor: | Carsten Bogh Juhl, Sabrina Mai Nielsen, Robin Christensen, Rinie Geenen, Berit Schiøttz-Christensen, Peter Thinggaard, Morten B Pedersen, Philip G. Conaghan, Kirstine Amris, Maarten de Wit, Anne Faber Hansen, Lyn March, Simon Tarp, Philip J. Mease, Lee S. Simon, Ernest Choy, Marianne U Rasmussen |
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| Jazyk: | angličtina |
| Rok vydání: | 2023 |
| Předmět: |
Biopsychosocial model
medicine.medical_specialty medicine.medical_treatment MEDLINE law.invention Findings tables Randomized controlled trial Quality of life Outpatient care Rheumatology law Rheumatoid-arthritis Educational-program Medicine Adverse effect Global burden Rehabilitation Hip business.industry Ankylosing-spondylitis Multidisciplinary team care Management Meta-analysis Physical therapy Patient-reported outcome Knee osteoarthritis business |
| Zdroj: | Arthritis care & research, 75(2), 423. John Wiley and Sons Inc. |
| ISSN: | 2151-464X |
| Popis: | Objective: To assess the benefits and harms associated with biopsychosocial rehabilitation in patients with inflammatory arthritis and osteoarthritis (OA). Methods: We performed a systematic review and meta-analysis. Data were collected through electronic searches of Cochrane CENTRAL, MEDLINE, Embase, PsycInfo, and CINAHL databases up to March 2019. Trials examining the effect of biopsychosocial rehabilitation in adults with inflammatory arthritis and/or OA were considered eligible, excluding rehabilitation adjunct to surgery. The primary outcome for benefit was pain and total withdrawals for harm. Results: Of the 27 trials meeting the eligibility criteria, 22 trials (3,750 participants) reported sufficient data to be included in the quantitative synthesis. For patient-reported outcome measures, biopsychosocial rehabilitation was slightly superior to control for pain relief (standardized mean difference [SMD] −0.19 [95% confidence interval (95% CI) −0.31, –0.07]), had a small effect on patient global assessment score (SMD –0.13 [95% CI –0.26, –0.00]), with no apparent effect on health-related quality of life, fatigue, self-reported disability/physical function, mental well-being, and reduction in pain intensity ≥30%. Clinician-measured outcomes displayed a small effect on observed disability/physical function (SMD −0.34 [95% CI −0.57, −0.10]), a large effect on physician global assessment score (SMD −0.72 [95% CI −1.18, −0.26]), and no effect on inflammation. No difference in harms existed in terms of the number of withdrawals, adverse events, or serious adverse events. Conclusion: Biopsychosocial rehabilitation produces a significant but clinically small beneficial effect on patient-reported pain among patients with inflammatory arthritis and OA, with no difference in harm. Methodologic weaknesses were observed in the included trials, suggesting low-to-moderate confidence in the estimates of effect. |
| Databáze: | OpenAIRE |
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