Low vitamin D exposure is associated with higher risk of infection in renal transplant recipients

Autor:	Michael A. Shullo, Puneet Sood, Raman Venkataramanan, Amit D. Tevar, Amanda I. Ingemi, Heather J. Johnson, Lauren M. Sacha, Hari V. Kalluri, Abhinav Humar
Rok vydání:	2017
Předmět:	Male medicine.medical_specialty Calcitriol medicine.medical_treatment 030230 surgery Infections Kidney Function Tests Rate ratio Gastroenterology 03 medical and health sciences Postoperative Complications 0302 clinical medicine Immune system Risk Factors Internal medicine Vitamin D and neurology Humans Medicine Longitudinal Studies Vitamin D Retrospective Studies Transplantation business.industry Incidence Incidence (epidemiology) Retrospective cohort study Middle Aged Prognosis Vitamin D Deficiency Kidney Transplantation Transplant Recipients United States Steroid hormone Cross-Sectional Studies Kidney Failure Chronic Female 030211 gastroenterology & hepatology business Follow-Up Studies Glomerular Filtration Rate medicine.drug
Zdroj:	Clinical Transplantation. 31:e12955
ISSN:	0902-0063
DOI:	10.1111/ctr.12955
Popis:	Background Vitamin D is a steroid hormone with multiple vital roles within the immune system. Various studies evaluated the influence of vitamin D on infections postrenal transplantation and found contrasting results. This study aimed to assess the relationship between vitamin D status and the incidence of infection in renal transplant recipients. Methods This is a retrospective cohort study of adult renal transplant recipients at the University of Pittsburgh Medical Center between 2005 and 2012. Patients were grouped as vitamin D sufficient (≥30 ng/mL) or deficient (
Databáze:	OpenAIRE
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