Baroreflex failure following radiation therapy for nasopharyngeal carcinoma
| Autor: | Wouter Wieling, John M. Karemaker, Jaques W. M. Lenders, Henri J L M Timmers |
|---|---|
| Přispěvatelé: | Other departments |
| Rok vydání: | 1999 |
| Předmět: |
Adult
Male medicine.medical_specialty Valsalva Maneuver medicine.medical_treatment Posture Pain Blood Pressure Baroreflex Hypotension Orthostatic The sympathoadrenal system and primary hypertension Heart Rate Internal medicine Antineoplastic Combined Chemotherapy Protocols Heart rate medicine Palpitations Humans Heart rate variability Het sympathoadrenale systeem en primaire hypertensie Cyclophosphamide Fatigue Denervation Radiotherapy Endocrine and Autonomic Systems business.industry Remission Induction Carotid sinus Nasopharyngeal Neoplasms Combined Modality Therapy Radiation therapy Methotrexate medicine.anatomical_structure Blood pressure Head and Neck Neoplasms Vincristine Lymphatic Metastasis Anesthesia Cardiology Neurology (clinical) medicine.symptom business |
| Zdroj: | Clinical Autonomic Research, 9, pp. 317-324 Clinical Autonomic Research, 9, 317-324 Clinical autonomic research, 9(6), 317-324. D. Steinkopff-Verlag |
| ISSN: | 0959-9851 |
| Popis: | The authors present a 51-year-old man with right-sided nasopharyngeal carcinoma who was treated for regional lymph node involvement by bilateral radiation therapy of the neck. Six years later he presented with episodic complaints of headache, flushing, and palpitations accompanied by elevations of blood pressure. Examination of arterial baroreflex function indicated selective afferent carotid sinus denervation. Cross spectral analysis of spontaneous heart rate and blood pressure variability showed decreased arterial baroreflex sensitivity (6.5 ms/mm Hg). Twenty-four hour measurements of blood pressure and heart rate variability showed labile hypertension during normal daytime activities. Baroreflex failure in this patient probably represents a late complication of bilateral radiation therapy of the neck. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full text from SpringerLink