Effect of CTA Tube Current on Spot Sign Detection and Accuracy for Prediction of Intracerebral Hemorrhage Expansion
| Autor: | Javier Romero, Anastasia Vashkevich, Jonathan Rosand, Rajiv Gupta, Michael J. Jessel, Alison Ayres, Joshua N. Goldstein, Andrea Morotti, Steven M. Greenberg, Anand Viswanathan, H. B Brouwers, Christopher D. Anderson, Mahmut Edip Gurol, K. Schwab |
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| Rok vydání: | 2016 |
| Předmět: |
Intracerebral hemorrhage
medicine.medical_specialty Future studies business.industry Diagnostic accuracy medicine.disease 030218 nuclear medicine & medical imaging 03 medical and health sciences 0302 clinical medicine Hematoma Text mining Radiation load Positive predicative value medicine Spot sign Radiology Nuclear Medicine and imaging Neurology (clinical) Radiology business 030217 neurology & neurosurgery |
| Zdroj: | AJNR. American journal of neuroradiology. 37(10) |
| ISSN: | 1936-959X |
| Popis: | BACKGROUND AND PURPOSE: Reduction of CT tube current is an effective strategy to minimize radiation load. However, tube current is also a major determinant of image quality. We investigated the impact of CTA tube current on spot sign detection and diagnostic performance for intracerebral hemorrhage expansion. MATERIALS AND METHODS: We retrospectively analyzed a prospectively collected cohort of consecutive patients with primary intracerebral hemorrhage from January 2001 to April 2015 who underwent CTA. The study population was divided into 2 groups according to the median CTA tube current level: low current ( RESULTS: This study included 709 patients (288 and 421 in the low- and high-current groups, respectively). A higher proportion of low-current scans identified at least 1 spot sign (20.8% versus 14.7%, P = .034), but hematoma expansion frequency was similar in the 2 groups (18.4% versus 16.2%, P = .434). Sensitivity and positive and negative predictive values were not significantly different between the 2 groups. Conversely, high-current scans showed superior specificity (91% versus 84%, P = .015) and overall accuracy (84% versus 77%, P = .038). CONCLUSIONS: CTA obtained at high levels of tube current showed better diagnostic accuracy for prediction of hematoma expansion by using spot sign. These findings may have implications for future studies using the CTA spot sign to predict hematoma expansion for clinical trials. |
| Databáze: | OpenAIRE |
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