Association of malalignment, muscular dysfunction, proprioception, laxity and abnormal joint loading with tibiofemoral knee osteoarthritis - A systematic review and meta-analysis

Autor: Joyce van Tunen, Andrea Dell'Isola, Martijn Steultjens, Hans Lund, Jonas Bloch Thorlund, Carsten Bogh Juhl, Joost Dekker
Přispěvatelé: Rehabilitation medicine, APH - Health Behaviors & Chronic Diseases, APH - Mental Health, AII - Inflammatory diseases, APH - Aging & Later Life
Jazyk: angličtina
Rok vydání: 2018
Předmět:
Male
lcsh:Diseases of the musculoskeletal system
Knee Joint
Sports medicine
knee
Osteoarthritis
medicine.disease_cause
Weight-bearing
Weight-Bearing
0302 clinical medicine
systematic review
Risk Factors
Muscle
Skeletal/physiopathology
Biomechanics
Orthopedics and Sports Medicine
Range of Motion
Articular
10. No inequality
Gait
Osteoarthritis
Knee/diagnosis
Middle Aged
Osteoarthritis
Knee
Prognosis
musculoskeletal system
Biomechanical Phenomena
Female
Research Article
Cohort study
Joint Instability
musculoskeletal diseases
medicine.medical_specialty
VDP::Medisinske Fag: 700::Helsefag: 800::Fysioterapi: 807
biomechanics
Knee Joint/physiopathology
03 medical and health sciences
Physical medicine and rehabilitation
Rheumatology
Internal medicine
medicine
Humans
Knee
Muscle
Skeletal
030203 arthritis & rheumatology
Proprioception
business.industry
Joint Instability/diagnosis
medicine.disease
VDP::Medisinske Fag: 700::Klinisk medisinske fag: 750::Reumatologi: 759
meta-analysis
Meta-analysis
osteoarthritis
Orthopedic surgery
Systematic review
lcsh:RC925-935
business
human activities
030217 neurology & neurosurgery
Zdroj: BMC Musculoskeletal Disorders
van Tunen, J A C, Dell'Isola, A, Juhl, C, Dekker, J, Steultjens, M, Thorlund, J B & Lund, H 2018, ' Association of malalignment, muscular dysfunction, proprioception, laxity and abnormal joint loading with tibiofemoral knee osteoarthritis-A systematic review and meta-analysis ', BMC Musculoskeletal Disorders, vol. 19, no. 1, 273 . https://doi.org/10.1186/s12891-018-2202-8
Van Tunen, J A C, Dell'Isola, A, Juhl, C, Dekker, J, Steultjens, M, Thorlund, J B & Lund, H 2018, ' Association of malalignment, muscular dysfunction, proprioception, laxity and abnormal joint loading with tibiofemoral knee osteoarthritis : A systematic review and meta-analysis ', BMC Musculoskeletal Disorders, vol. 19, no. 1, 273 . https://doi.org/10.1186/s12891-018-2202-8
BMC Musculoskeletal Disorders, 19(1):273. BioMed Central
BMC Musculoskeletal Disorders, Vol 19, Iss 1, Pp 1-15 (2018)
ISSN: 1471-2474
DOI: 10.1186/s12891-018-2202-8
Popis: Background: To investigate (1) the association of specific biomechanical factors with knee osteoarthritis and knee osteoarthritis development, and (2) the impact of other relevant risk factors on this association.Methods: MEDLINE, EMBASE, CINAHL and SPORTDiscus were searched up until April 2017. Studies were included if they fulfilled the following criteria: the study 1) assessed the association of a biomechanical factor with knee osteoarthritis, or knee osteoarthritis development; 2) reported on skeletal malalignment, muscular dysfunction, impaired proprioception, laxity and abnormal loading during gait; 3) was a cohort study with participants developing knee osteoarthritis and participants not developing knee osteoarthritis, or a case-control or cross-sectional study with participants with knee osteoarthritis and without knee osteoarthritis. Risk of bias was assessed with the QUIPS tool and meta-analyses were performed using random effects models.Results: Of 6413 unique studies identified, 59 cross-sectional studies were eligible for meta-analyses (9825 participants, 5328 with knee osteoarthritis). No cohort studies fulfilled the inclusion criteria. Compared with healthy controls, patients with knee osteoarthritis have higher odds of having lower muscle strength, proprioception deficits, more medial varus-valgus laxity and less lateral varus-valgus laxity. Patients with medial knee osteoarthritis have higher odds of having a higher knee adduction moment than healthy controls. Level of evidence was graded as 'very low' to 'moderate' quality. Due to large between study differences moderation of other risk factors on biomechanical risk factors could not be evaluated.Conclusions: Patients with knee osteoarthritis are more likely to display a number of biomechanical characteristics. The causal relationship between specific biomechanical factors and the development of knee osteoarthritis could not be determined as no longitudinal studies were included. There is an urgent need for high quality, longitudinal studies to evaluate the impact of specific biomechanical factors on the development of knee osteoarthritis.Trial Registration: (PROSPERO ID: CRD42015025092).
Databáze: OpenAIRE
Externí odkaz: