Diuretic-induced hypokalaemia inducing torsades de pointes

Autor: Gary E. Hill, Jeffrey P. Chvilicek, Barbara J. Hurlbert
Rok vydání: 1995
Předmět:
Zdroj: Canadian Journal of Anaesthesia. 42:1137-1139
ISSN: 1496-8975
0832-610X
DOI: 10.1007/bf03015102
Popis: Torsades de pointes (TP), an unique polymorphous type of ventricular tachycardia, is associated with either an acquired or congenitally prolonged QT interval. Several reports have demonstrated TP to follow an acquired prolonged QT interval secondary to chronic hypocalcaemia, hypomagnesaemia, or hypokalaemia. We report a rapid onset, acute extracellular hypokalaemia not associated with other electrolyte disturbances inducing a prolonged QT interval followed by TP. This is the first case report of a rapid onset isolated acute extracellular hypokalaemia inducing TP. Since anaesthetists are involved in therapies that will rapidly reduce extracellular potassium (diuretic, catecholamine, and/or insulin administration, hyperventilation), this case report serves as a warning that such therapy may have the risk of arrhythmia induction.
Databáze: OpenAIRE