Role of mitochondria in calcium signalling in mammalian sensory neurons

Autor:	N. V. Svichar, P. G. Kostyuk, E. P. Kostyuk, V. O. Shishkin, Nana Voitenko
Rok vydání:	1998
Předmět:	Physiology General Neuroscience chemistry.chemical_element Depolarization Calcium Mitochondrion Biology Cell biology Cell membrane Cytosol medicine.anatomical_structure chemistry Dorsal root ganglion medicine Intracellular Calcium signaling
Zdroj:	Scopus-Elsevier
ISSN:	1573-9007 0090-2977
DOI:	10.1007/bf02462810
Popis:	Calcium signals evoked at depolarization of the cell membrane and their modifications induced by blocking of accumulation of these ions in the mitochondria and blocking of mitochondrial Na+/Ca2+ exchange were studied in dorsal root ganglion neurons of mice with the use of fluorescent measurements of shifts in the intracellular Ca2+ level. Mitochondria aredemonstrated to be actively involved in formation of these signals by rapid peak absorption of Ca ions from and their subsequent return to the cytosol.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4bdfc242193a9e4e5bc432c24d57bb9 https://doi.org/10.1007/bf02462810 Zobrazit plný text záznamu Full text from SpringerLink