The association between body mass index and varicocele: A meta-analysis
| Autor: | Huang Zhi-Peng, Guo Wenbin, Xia Hui, Cai Zhi-Xuan, Guo Xiao-Bin, Wu Fang-Lei, Liu Cundong, Yang Cheng |
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| Rok vydání: | 2021 |
| Předmět: |
Male
medicine.medical_specialty Urology Varicocele 030232 urology & nephrology Review Article Overweight Lower risk Body Mass Index 03 medical and health sciences 0302 clinical medicine Risk Factors Internal medicine Humans Medicine Meta-Analysis [Publication Type] Obesity business.industry Odds ratio medicine.disease Diseases of the genitourinary system. Urology 030220 oncology & carcinogenesis Meta-analysis Population study RC870-923 Underweight medicine.symptom business Body mass index |
| Zdroj: | International Brazilian Journal of Urology : official journal of the Brazilian Society of Urology International braz j urol, Volume: 47, Issue: 1, Pages: 19-8, Published: 18 NOV 2020 International Brazilian Journal of Urology, Vol 47, Iss 1, Pp 8-19 (2020) International braz j urol v.47 n.1 2021 International Braz J Urol Sociedade Brasileira de Urologia (SBU) instacron:SBU |
| ISSN: | 1677-6119 1677-5538 |
| DOI: | 10.1590/s1677-5538.ibju.2019.0210 |
| Popis: | Objective: Recently, several studies have found that obesity had a protective effect against varicocele, but no meta-analysis has confirmed this finding. Therefore, we conducted this meta-analysis to investigate the association between body mass index (BMI) and varicocele. Material and Methods: We searched for studies in PubMed, Science Direct and the Cochrane Library from inception until February 2018. The association between BMI and varicocele was assessed by pooling the odds ratios (ORs). Results: Eleven eligible studies with a total study population of 1.376.658 participants were included in our analysis. According to BMI, the subjects were defined as belonging to the obese, overweight and underweight groups. Our results showed that the obese group had a lower risk of varicocele when compared with the normal weight group (odds ratio [OR] 0.46, 95% confidence intervals [CIs] 0.37-0.58). Additionally, an overweight BMI had a protective effect against varicocele (OR 0.70, 95% CIs, 0.56-0.86). However, underweight patients had a more than 30% higher risk of varicocele (OR 1.31, 95% CI, 1.04-1.64). Furthermore, there was no publication bias in any of the analyses. Conclusions: Our study demonstrates that BMI is negatively associated with the presence of varicocele. |
| Databáze: | OpenAIRE |
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