Laboratory-based Surveillance for Hepatitis E Virus Infection, United States, 2005–2012

Autor: Drobeniuc, Jan, Greene-Montfort, Tracy, Le, Ngoc-Thao, Mixson-Hayden, Tonya R., Ganova-Raeva, Lilia, Dong, Chen, Novak, Ryan T., Sharapov, Umid M., Tohme, Rania A., Teshale, Eyasu, Kamili, Saleem, Teo, Chong-Gee
Jazyk: angličtina
Rok vydání: 2013
Předmět:
Male
Genes
Viral
Epidemiology
viruses
lcsh:Medicine
Antibodies
Viral
medicine.disease_cause
Unites States
jaundice
Hepatitis E virus
CME
differential diagnosis
Genotype
Prevalence
Young adult
Phylogeny
travel
diagnostic techniques
Incidence (epidemiology)
Middle Aged
Jaundice
Hepatitis E
Infectious Diseases
Epidemiological Monitoring
surveillance
RNA
Viral
Female
travel-related infections
medicine.symptom
Adult
Microbiology (medical)
medicine.medical_specialty
Adolescent
hepatitis E virus
Article
lcsh:Infectious and parasitic diseases
Young Adult
Internal medicine
medicine
Humans
lcsh:RC109-216
Aged
immunocompromised host
Hepatitis
business.industry
Research
lcsh:R
Sequence Analysis
DNA
infectious disease transmission
medicine.disease
Virology
United States
HEV
incidence
business
human activities
Hepatitis E virus infection
Zdroj: Emerging Infectious Diseases, Vol 19, Iss 2, Pp 218-222 (2013)
Emerging Infectious Diseases
ISSN: 1080-6059
1080-6040
Popis: Clinicians should consider this virus in the differential diagnosis of hepatitis, regardless of patient travel history.
To investigate characteristics of hepatitis E cases in the United States, we tested samples from persons seronegative for acute hepatitis A and B whose clinical specimens were referred to the Centers for Disease Control and Prevention during June 2005–March 2012 for hepatitis E virus (HEV) testing. We found that 26 (17%) of 154 persons tested had hepatitis E. Of these, 15 had not recently traveled abroad (nontravelers), and 11 had (travelers). Compared with travelers, nontravelers were older (median 61 vs. 32 years of age) and more likely to be anicteric (53% vs. 8%); the nontraveler group also had fewer persons of South Asian ethnicity (7% vs. 73%) and more solid-organ transplant recipients (47% vs. 0). HEV genotype 3 was characterized from 8 nontravelers and genotypes 1 or 4 from 4 travelers. Clinicians should consider HEV infection in the differential diagnosis of hepatitis, regardless of patient travel history.
Databáze: OpenAIRE
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