Association of Serum Osmolarity With Contrast-Induced Nephropathy in Patients With ST-Segment Elevation Myocardial Infarction

Autor: Yavuz Karabağ, Metin Çağdaş, İbrahim Yıldız, Pinar Ozmen Yildiz, Mehmet Sait Gurevin, Cengiz Burak, İbrahim Rencüzoğulları
Rok vydání: 2019
Předmět:
Adult
Male
0301 basic medicine
medicine.medical_specialty
medicine.medical_treatment
Contrast-induced nephropathy
Contrast Media
030204 cardiovascular system & hematology
Coronary Angiography
Risk Assessment
Nephropathy
03 medical and health sciences
chemistry.chemical_compound
Percutaneous Coronary Intervention
0302 clinical medicine
Predictive Value of Tests
Risk Factors
Internal medicine
Humans
Medicine
ST segment
Myocardial infarction
Aged
Retrospective Studies
Creatinine
Ejection fraction
business.industry
Osmolar Concentration
Percutaneous coronary intervention
Middle Aged
medicine.disease
female genital diseases and pregnancy complications
Treatment Outcome
surgical procedures
operative
030104 developmental biology
chemistry
Cardiology
ST Elevation Myocardial Infarction
Female
Kidney Diseases
Cardiology and Cardiovascular Medicine
business
Kidney disease
Zdroj: Angiology. 70:627-632
ISSN: 1940-1574
0003-3197
Popis: Contrast-induced nephropathy (CIN) is a prevalent and serious complication after primary percutaneous coronary intervention (pPCI). Although the association between serum osmolarity and chronic kidney disease is well established, its relation to CIN in patients with ST-segment elevation myocardial infarction (STEMI) undergoing pPCI needs to be elucidated. We evaluated the predictive value of serum osmolarity for CIN development in patients with STEMI (n = 768) undergoing pPCI. Serum osmolarity on admission was calculated. The study population was divided into 2 groups according to CIN development, and both groups were compared according to clinical, laboratory, and demographic features, including the serum osmolarity. Serum osmolarity was significantly higher in patients with CIN than in those without CIN (278 [8] vs 284 [9]; P = .024). Serum osmolarity (odds ratio: 1.052; 95% confidence interval: 1.018-1.086; P = .002), hemoglobin, contrast media volume, creatinine on admission, basal SYNergy between PCI with TAXus and cardiac surgery II score, and left ventricular ejection fraction were found to be independent predictors of CIN. Serum osmolarity (given the simple calculation of this parameter on admission) can be useful to define patients with STEMI undergoing pPCI who are more likely to develop CIN.
Databáze: OpenAIRE
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