Diagnostic Delays in Metastatic Amelanotic Melanoma Presenting as Breast Pain
| Autor: | Raisa Epistola, Duong T. Hua, Tiffanie Do, Maria M. Taylor, Rose Venegas |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
Delayed Diagnosis Skin Neoplasms Breast imaging medicine.medical_treatment Breast pain Breast Neoplasms Biopsy medicine Mammography Humans Amelanotic melanoma Melanoma Mastectomy medicine.diagnostic_test business.industry Mediastinum Melanoma Amelanotic General Medicine Articles Middle Aged medicine.disease medicine.anatomical_structure Female Radiology medicine.symptom business Mastodynia |
| Zdroj: | The American Journal of Case Reports |
| ISSN: | 1941-5923 |
| Popis: | Patient: Female, 58-year-old Final Diagnosis: Metastatic amelanotic melanoma Symptoms: Breast mass • breast pain Medication: — Clinical Procedure: Mastectomy Specialty: Dermatology • Oncology Objective: Rare disease Background: Breast metastases from melanoma are rare. Amelanotic melanoma is difficult to diagnose, as primary lesions not only lack the pigment typical of melanoma, but also lack other features associated with these tumors, including asymmetry, irregular borders, and color variegation. Case Report: A 58-year-old woman presented with an enlarging mass on her left breast, a finding confirmed by physical examination. Mammography showed a 10-cm breast mass of category 4 according to the Breast Imaging Reporting and Data System (BI-RADS). Staging computed tomography (CT) showed widely scattered metastatic sites in the brain, lungs, mediastinum, and adrenal glands. A biopsy of the mass in her left breast was non-diagnostic due to extensive necrosis. Because of severe pain, simple left breast mastectomy was performed. Tissue from the mastectomy revealed a diagnosis of amelanotic malignant melanoma. Conclusions: Diagnosing amelanotic melanoma is difficult without tissue biopsy as these tumors lack the typical features of melanoma and can mimic other dermatologic diseases. This frequently results in a significant delay in diagnosing amelanotic melanoma, with patients often presenting with advanced stage disease having poor prognosis. |
| Databáze: | OpenAIRE |
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