Iodine-125 plaque brachytherapy for diffuse choroidal hemangioma

Autor: Corrina P. Azarcon, Richard L.J. Qiu, Ethan K. Sobol, G. Baker Hubbard, Caroline M. Craven, Chris S. Bergstrom, Jill R. Wells
Rok vydání: 2022
Předmět:
Zdroj: Retinal casesbrief reports.
ISSN: 1937-1578
Popis: To report 6 cases of diffuse choroidal hemangioma (DCH) in children treated with iodine-125 plaque brachytherapy at a single tertiary care center.Retrospective case series.Six pediatric patients diagnosed with DCH were included in the study. Pre-plaque visual acuity (VA) ranged from 20/150 to no light perception (NLP). All patients had extensive serous retinal detachment at presentation. An iodine-125 radioactive plaque was placed on the affected eye to administer a dose of 34.2-42.1 Gy to the tumor apex over a median of 4 days. Tumor regression and subretinal fluid resolution were observed in all eyes within 17 months of treatment. Visual acuity improved in 2 patients. Radiation-induced cataract and subretinal fibrosis were documented in 1 case, and 1 patient developed radiation retinopathy. No patients developed neovascular glaucoma within a follow-up range of 12-65 months.Iodine-125 plaque radiotherapy is an effective option for DCH, although there is a risk for radiation-induced complications.
Databáze: OpenAIRE