Cutting-balloon angioplasty effectively facilitates the interventional procedure and leads to a low rate of recurrent stenosis in ostial bifurcation coronary lesions: A subgroup analysis of the NICECUT multicenter registry
| Autor: | Johannes B. Dahm, Astrid Hummel, Marcus Dörr, Elisabeth Scholz, Jörg Ruppert, Stephan B. Felix, Alexander Staudt |
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| Rok vydání: | 2008 |
| Předmět: |
Adult
Male medicine.medical_specialty medicine.medical_treatment Coronary Angiography Balloon Coronary Restenosis Electrocardiography Restenosis Germany Multicenter trial Internal medicine Angioplasty medicine Clinical endpoint Humans Angioplasty Balloon Coronary Aged Retrospective Studies business.industry Middle Aged medicine.disease Stenosis Treatment Outcome Cardiology Female Cutting balloon Radiology Cardiology and Cardiovascular Medicine business Mace Follow-Up Studies |
| Zdroj: | International Journal of Cardiology. 124:345-350 |
| ISSN: | 0167-5273 |
| DOI: | 10.1016/j.ijcard.2007.02.014 |
| Popis: | Background Displacement of plaque is a major concern during coronary intervention of ostial bifurcation lesions. For this reason, angioplasty involves complex stenting procedures, which may trigger development of restenosis in a previously non-diseased parent vessel. Objectives To examine, whether plaque displacement may be prevented by scoring atherosclerotic plaque with a cutting-balloon (CB) stand-alone procedure. Methods Data of patients with Duke E and B type ostial bifurcation lesions (≥70% stenosis involving a diagonal and/or marginal branch >2 mm deriving from a non-diseased parent vessel), who were treated with CB as stand-alone procedure within the prospective NICECUT multicenter trial were analyzed. Primary endpoint was the rate of binary stenosis and target lesion revascularization (TLR). Secondary endpoints were procedural success and major adverse cardiac events (MACE) at 6-months follow-up. Results 63 out of 65 lesions (56 patients) were successfully amenable to treatment with CB (96.4% procedural success). 76.9% of patients were successfully treated with CB as a stand-alone procedure, while provisional stenting was necessary in 23.1%. At follow-up, binary stenosis was found in 23.2%, among the total population. Total rate of TLR and MACE were 7.7% and 3.6%, respectively, compared to 4.0% and 2.0% in patients for whom CB stand-alone procedure was feasible, while it was 20.0% and 6.7% for stented lesions. Conclusions CB angioplasty as a stand-alone procedure may facilitate interventional treatment of ostial bifurcation lesions and may help to avoid complex stenting procedures. It is associated with a low rate of binary stenosis and TLR. |
| Databáze: | OpenAIRE |
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