Outpatient benzodiazepine detoxification procedure for methadone patients
| Autor: | Robert P. Schwartz, Timothy Donovan, Anthony Tommasello, David R. McDuff, Stuart A. Tiegel, Jeannette L. Johnson |
|---|---|
| Rok vydání: | 1993 |
| Předmět: |
Adult
Male Methadone maintenance Substance-Related Disorders medicine.drug_class media_common.quotation_subject Population Medicine (miscellaneous) Drug Administration Schedule Benzodiazepines Ambulatory Care medicine Humans education media_common Benzodiazepine education.field_of_study Dose-Response Relationship Drug business.industry Addiction Middle Aged Opioid-Related Disorders Combined Modality Therapy Substance Withdrawal Syndrome Substance Abuse Detection Psychiatry and Mental health Clinical Psychology Anti-Anxiety Agents Alprazolam Opioid Anesthesia Female Pshychiatric Mental Health business Diazepam Methadone Follow-Up Studies medicine.drug |
| Zdroj: | Journal of Substance Abuse Treatment. 10:297-302 |
| ISSN: | 0740-5472 |
| Popis: | Benzodiazepines are used by a substantial minority of opioid addicts on methadone maintenance. Alprazolam, now the most widely prescribed benzodiazepine in the United States, appears to have supplanted diazepam as the benzodiazepine drug of choice in this population. Its greater addiction liability, shorter half-life, and more intense withdrawal symptoms make addiction to alprazolam more likely and its management in methadone patients more complicated. This article describes a slow outpatient tapered reduction procedure that was utilized to detoxify benzodiazepine dependent methadone patients seen over a two-year period. The reduction procedure was offered to 22 opioid addicts on methadone maintenance who were regularly ingesting low to moderate amounts of benzodiazepines, primarily alprazolam. Of the 22 patients, 4 patients refused outpatient detoxification, and 18 were started on a reduction procedure. Twelve patients completed the detoxification procedure which averaged 7.8 weeks. Comparisons are made between completers and non-completers and essential design features of the procedure are discussed. |
| Databáze: | OpenAIRE |
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