The neural circuitry of reward and its relevance to psychiatric disorders
| Autor: | Robert M. Roth, Alan I. Green, David T. Chau |
|---|---|
| Rok vydání: | 2004 |
| Předmět: |
medicine.medical_specialty
media_common.quotation_subject Receptors Dopamine Reward Functional neuroimaging Animals Laboratory medicine Biological neural network Animals Humans Psychiatry media_common Mental Disorders Brain medicine.disease Magnetic Resonance Imaging Disease Models Animal Psychiatry and Mental health Reward dependence Schizophrenia Positron-Emission Tomography Major depressive disorder Curiosity Brain stimulation reward Psychology psychological phenomena and processes Electrical brain stimulation |
| Zdroj: | Current Psychiatry Reports. 6:391-399 |
| ISSN: | 1535-1645 1523-3812 |
| Popis: | Scientific interest in how the brain processes reward has burgeoned during the past 50 years since the discovery that rats will do tasks such as pressing a lever to obtain electrical stimulation of the brain. This interest was additionally encouraged by the observation of an association between reward and dopamine activity in the mesocorticolimbic system. In this article, we will discuss the complex nature of reward processing and recent animal studies and human functional neuroimaging studies to elucidate the current understanding of the neural substrates of reward processing and its components. Lastly, we will review recent theoretical and empirical work investigating the role of brain reward circuitry in several psychiatric disorders, including substance use disorders, schizophrenia, pathologic gambling, major depressive disorder, and attention-deficit/hyperactivity disorder. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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