Low Grade Neuroendocrine Tumors of the Lung
| Autor: | Barbara Melosky |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
Oncology
Cancer Research medicine.medical_specialty Pathology octeotride Mini Review Context (language use) 030204 cardiovascular system & hematology Neuroendocrine tumors lcsh:RC254-282 Systemic therapy lung 03 medical and health sciences 0302 clinical medicine Internal medicine medicine Everolimus Lung business.industry Effective management Atypical carcinoid lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens medicine.disease everolimus Carcinoid Somatostatin medicine.anatomical_structure 030220 oncology & carcinogenesis neuroendocrine tumors business medicine.drug |
| Zdroj: | Frontiers in Oncology Frontiers in Oncology, Vol 7 (2017) |
| ISSN: | 2234-943X |
| Popis: | The lung is the second most common site of neuroendocrine tumours (NETs). Typical and atypical carcinoid are low grade neuroendocrine tumors of the lung. They present a favorable prognosis comported to the more common high grade neuroendocrine tumors. The low and high grade NETS require different treatment strategies; effective management of these tumours is essential to prolong survival and to manage the symptoms in patients with secretory or functional tumours. These rare tumours have received little attention and education is needed for treating physicians. This mini-review will concentrate mainly on advanced low-grade lung NETs. The article describes the classification of lung NETs and the diagnostic work-up. Different treatment methods including somatostatin analogues, peptide receptor radioligand therapy and biologic systemic therapy are discussed. Promising results from recent trials are presented and discussed in the context of the lung primary site. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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