Excretion of alpha-chaconine-3H, a steroidal glycoalkaloid from Solanum tuberosum L. and its metabolites in hamsters

Autor:	Raghubir P. Sharma, D. K. Salunkhe, Sydney O. Alozie
Rok vydání:	1979
Předmět:	Pharmacology Chromatography Time Factors Solanine Mesocricetus Urine Thin-layer chromatography Solanidine Excretion chemistry.chemical_compound Feces chemistry Glycoalkaloid Cricetinae Animals Chaconine
Zdroj:	Pharmacological research communications. 11(6)
ISSN:	0031-6989
Popis:	Excretion of α-chaconine-( 3 H) and its metabolites was investigated after oral and intraperitoneal administration in hamsters. The separation of the glycoalkaloid and its metabolites in feces and urine was accomplished by thin layer chromatography and strip counting technique. An increase in the concentration of excreted α-chaconine and its metabolites in feces and urine was observed with time. In urine over 50% of the eliminated radioactivity during the initial 24 hr was due to unaltered α-chaconine and solanidine, and the fraction of the total dose administered which was excreted represented approximately
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b48b383ee15dbf43b3dbb2b3ebe2c19e https://pubmed.ncbi.nlm.nih.gov/504322 Zobrazit plný text záznamu