Unrestrained eating behavior and risk of mortality: A prospective cohort study
| Autor: | Kimmie Ng, Edward Giovannucci, Andrew T. Chan, Mingyang Song, Chen Yuan, Walter C. Willett, Jeffrey A. Meyerhardt, Eva S. Schernhammer, Brian M. Wolpin, Charles S. Fuchs, Frank B. Hu, Eric B. Rimm, Susan B. Roberts, Yin Zhang, Meir J. Stampfer |
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| Rok vydání: | 2021 |
| Předmět: |
Adult
Male medicine.medical_specialty Respiratory Tract Diseases Critical Care and Intensive Care Medicine Article Risk Factors Cause of Death Neoplasms Internal medicine Risk of mortality medicine Humans Prospective Studies Lung cancer Prospective cohort study Aged Proportional Hazards Models Nutrition and Dietetics Proportional hazards model business.industry Hazard ratio Respiratory disease Cancer Feeding Behavior Middle Aged medicine.disease Confidence interval Diet Cardiovascular Diseases Female business Follow-Up Studies |
| Zdroj: | Clin Nutr |
| ISSN: | 0261-5614 |
| Popis: | Summary Background & aims Unrestrained eating behavior has been thought to be a proxy for diet frequency, timing, and caloric intake. We investigated the association of unrestrained eating with mortality risk in the Nurses’ Health Study prospectively. Methods During follow-up (1994–2016), 21,953 deaths were documented among 63,999 eligible participants in analyses of eating anything at any time, 22,120 deaths were documented among 65,839 participants in analyses of no concern with figure change. Hazard ratios (HRs) and 95% confidence intervals (CIs) were calculated using Cox proportional hazards models. Results Eating anything at any time was associated with an increased mortality from cancer (overall HR, 95%CI: 1.07, 1.00–1.13; driven by gastrointestinal tract cancer: 1.30, 1.10–1.54) and respiratory disease (1.16, 1.05–1.29), and decreased cardiovascular disease-specific mortality (0.92, 0.86–0.99), compared to those without this behavior; however, no association was observed between this behavior and all-cause mortality (1.02, 0.99–1.05). Women who reported having no concern with figure change experienced higher risk of mortality from all-cause (1.08, 1.05–1.11), cancer (1.08, 1.02–1.14), and respiratory disease (1.18, 1.08–1.30), compared to those not reporting this behavior. Their combined effect was associated with a higher all-cause (1.09, 1.04–1.14), cancer-specific (overall: 1.18, 1.09–1.28; gastrointestinal tract cancer: 1.36, 1.08–1.71; lung cancer: 1.09; 1.04–1.14), and respiratory disease-specific (1.30, 1.13–1.50) mortality, and was inversely associated with cardiovascular disease-specific mortality (0.88, 0.80–0.98), compared to those exhibiting the opposite. Conclusions Unrestrained eating was associated with increased risk of all-cause, cancer-specific (particularly for gastrointestinal tract cancer and lung cancer), and respiratory disease-specific mortality, and decreased risk of cardiovascular disease-specific mortality. |
| Databáze: | OpenAIRE |
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