Abnormal pregnancy: early diagnosis by US and serum chorionic gonadotropin levels

Autor: Dakir L. Duarte Filho, David A. Nyberg, Barry S. Mahoney, Faye C. Laing, Roy A. Filly
Rok vydání: 1986
Předmět:
Zdroj: Radiology. 158:393-396
ISSN: 1527-1315
0033-8419
DOI: 10.1148/radiology.158.2.3510444
Popis: Simultaneous sonography and quantitative serum human chorionic gonadotropin (HCG) levels from 126 women with threatened abortion were compared. Of 56 women with normal outcome, 39 (70%) had a gestation sac greater than or equal to 5 mm in mean sac diameter, and in each case the HCG level was 1,800 milli-international units (mIU/ml) or greater. The serum HCG levels strongly correlated with the gestation sac sizes to a mean sac diameter of 25 mm. Of 70 abnormal pregnancies, 31 demonstrated a gestation sac. Of these, 20 women (65%) had disproportionately low HCG levels relative to sac size, including 12 in whom the HCG level was less than 1,800 mIU/ml. One woman with an early molar pregnancy had a disproportionately elevated HCG level. Correlation of sonograms with a simultaneous measurement of serum HCG level is a useful method for evaluating threatened spontaneous abortion. A disproportionately low HCG level relative to gestation sac size is evidence for an abnormal pregnancy.
Databáze: OpenAIRE