Digital orbitoplethysmograph: A new device to study the regional cerebral circulation using extraorbital plethysmography
| Autor: | Vladimir Masin, Jan Kremlacek, Petr Voda, Tomas Hosszu, Owen Falzon, Mikulás Vachek, Kenneth P. Camilleri, Ales Bezrouk, Jiří Záhora |
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| Rok vydání: | 2019 |
| Předmět: |
0301 basic medicine
Electroencephalography 03 medical and health sciences Cerebral circulation 0302 clinical medicine Pulse wave Medicine Plethysmograph Humans Reliability (statistics) Intracranial pressure medicine.diagnostic_test business.industry General Neuroscience Reproducibility of Results Equipment Design Collateral circulation Transcranial Doppler Plethysmography 030104 developmental biology Regional Blood Flow Cerebrovascular Circulation Pulsatile Flow Circle of Willis business Orbit 030217 neurology & neurosurgery Biomedical engineering |
| Zdroj: | Journal of neuroscience methods. 329 |
| ISSN: | 1872-678X |
| Popis: | Background Noninvasive diagnostic methods utilizing pulse wave measurements on the surface of the head are an important tool in diagnosing various types of cerebrovascular disease. The measurement of extraorbital pressure fluctuations reflects intraocular and intracranial pressure changes and can be used to estimate pressure changes in intracranial arteries and the collateral circulation. New Method In this paper, we describe our patented (CZ 305757) digital device for noninvasive measuring and monitoring of orbital movements using pressure detection. We conducted preclinical tests (126 measurements on 42 volunteers) to evaluate the practical capabilities of our device. Two human experts visually assessed the quality of the pressure pulsation and discriminability among various test conditions (specifically, subject lying, sitting, and the Matas carotid occlusion test). Results The results showed that our device provided clinically relevant outcomes with a sufficient level of detail of the pulse wave and a high reliability (not less than 85%) in all clinically relevant situations. It was possible to record the effect of the Matas carotid occlusion test. Comparison with Existing Method(s) Our fully noninvasive, lightweight (185 g), portable, and wireless device provides a considerably cheaper alternative to the current diagnostic methods (e.g., transcranial ultrasound, X-ray, or MRI angiography) for specific assessment of cerebral circulation. Within a minute, it can detect the Willis circle integrity and thus eliminate the potential risks associated with the Matas test using standard EEG. Conclusions Our device represents an improvement and a valid alternative to the current methods diagnosing regional cerebral circulation. |
| Databáze: | OpenAIRE |
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