The association of COVID-19 infection in pregnancy with preterm birth: A retrospective cohort study in California
| Autor: | Jodi Stookey, Kayla L. Karvonen, Xianhua Piao, Joan A. Casey, Matthew S. Pantell, Laura L. Jelliffe-Pawlowski, Miriam Kuppermann, Rebecca J. Schmidt, Kimberly Coleman-Phox, Jennifer N. Felder, Karen A. Scott, Rebecca J. Baer, Anu Manchikanti Gomez, Jonathan D. Fuchs, Larry Rand, Charles E. McCulloch, Scott P. Oltman, Deborah Karasek, Liang Liang, Jean Costello, Monica R. McLemore, Safyer McKenzie-Sampson, Solaire Spellen, Bridgette E. Blebu, Martha A. Tesfalul, April J. Bell, Elena Flowers, Aric A. Prather |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Coronavirus disease 2019 (COVID-19)
Ethnic group Disease Reproductive health and childbirth Low Birth Weight and Health of the Newborn Preterm Birth Preterm Clinical Research Pregnancy Diabetes mellitus Infant Mortality Medicine Racial/Ethnic Inequities Pediatric Racial business.industry Prevention Contraception/Reproduction Gestational age COVID-19 Retrospective cohort study Perinatal Period - Conditions Originating in Perinatal Period medicine.disease Ethnic Inequities Obesity Increased risk Good Health and Well Being Pacific islanders Public aspects of medicine RA1-1270 business Demography Research Paper |
| Zdroj: | Lancet Regional Health. Americas The Lancet Regional Health. Americas, Vol 2, Iss, Pp 100027-(2021) |
| ISSN: | 2667-193X |
| Popis: | Author(s): Karasek, Deborah; Baer, Rebecca J; McLemore, Monica R; Bell, April J; Blebu, Bridgette E; Casey, Joan A; Coleman-Phox, Kimberly; Costello, Jean M; Felder, Jennifer N; Flowers, Elena; Fuchs, Jonathan D; Gomez, Anu Manchikanti; Karvonen, Kayla; Kuppermann, Miriam; Liang, Liang; McKenzie-Sampson, Safyer; McCulloch, Charles E; Oltman, Scott P; Pantell, Matthew S; Piao, Xianhua; Prather, Aric A; Schmidt, Rebecca J; Scott, Karen A; Spellen, Solaire; Stookey, Jodi D; Tesfalul, Martha; Rand, Larry; Jelliffe-Pawlowski, Laura L | Abstract: IntroductionOur understanding of the association between coronavirus disease 19 (COVID-19) and preterm or early term birth among racially and ethnically diverse populations and people with chronic medical conditions is limited.MethodsWe determined the association between COVID-19 and preterm (PTB) birth among live births documented by California Vital Statistics birth certificates between July 2020 and January 2021 (n=240,147). We used best obstetric estimate of gestational age to classify births as very preterm (VPTB, l32 weeks), PTB (l 37 weeks), early term (37 and 38 weeks), and term (39-44 weeks), as each confer independent risks to infant health and development. Separately, we calculated the joint effects of COVID-19 diagnosis, hypertension, diabetes, and obesity on PTB and VPTB.FindingsCOVID-19 diagnoses on birth certificates increased for all racial/ethnic groups between July 2020 and January 2021 and were highest for American Indian/Alaska Native (12.9%), Native Hawaiian/Pacific Islander (11.4%), and Latinx (10.3%) birthing people. COVID-19 diagnosis was associated with an increased risk of VPTB (aRR 1.6, 95% CI [1.4, 1.9]), PTB (aRR 1.4, 95% CI [1.3, 1.4]), and early term birth (aRR 1.1, 95% CI [1.1, 1.2]). There was no effect modification of the overall association by race/ethnicity or insurance status. COVID-19 diagnosis was associated with elevated risk of PTB in people with hypertension, diabetes, and/or obesity.InterpretationIn a large population-based study, COVID-19 diagnosis increased the risk of VPTB, PTB, and early term birth, particularly among people with medical comorbidities. Considering increased circulation of COVID-19 variants, preventative measures, including vaccination, should be prioritized for birthing persons.FundingUCSF-Kaiser Department of Research Building Interdisciplinary Research Careers in Women's Health Program (BIRCWH) National Institute of Child Health and Human Development (NICHD) and the Office of Research on Women's Health (ORWH) [K12 HD052163] and the California Preterm Birth Initiative, funded by Marc and Lynn Benioff. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|