Lignanamides from the stems of Piper hancei maxim. and their anti-inflammatory and cytotoxic activities

Autor:	Fan Yang, Hua Li, Yan-Qiu Yang, Yue Hou, Dong Liang
Rok vydání:	2022
Předmět:	Pharmacology Molecular Structure Drug Discovery Anti-Inflammatory Agents Humans Antineoplastic Agents General Medicine Piper HeLa Cells
Zdroj:	Fitoterapia. 161:105231
ISSN:	0367-326X
DOI:	10.1016/j.fitote.2022.105231
Popis:	Four new lignanamides, hancamides A - D (1-4), together with four known analogs (5-8), were isolated from the stems of Piper hancei Maxim. Their structures were determined based on 1D and 2D NMR, IR, UV, and HR-ESIMS spectroscopic analysis as well as by comparison with the reported data. All the isolates exhibited potential inhibitory effects on NO production in LPS-induced BV-2 microglial cells, with IC
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b47e25ebc1adebf38896a8475366702d https://doi.org/10.1016/j.fitote.2022.105231 Zobrazit plný text záznamu Full Text from ScienceDirect