Adolescent gynecomastia is associated with a high incidence of obesity, dysglycemia, and family background of diabetes mellitus
| Autor: | Deep Dutta, Patnaik T Rajesh, Sharma Neera, Bindu Kulshreshtha, Arora Arpita, Bhattacharya Sameek, Mohsin Mohd |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: |
Pediatrics
medicine.medical_specialty obesity Adolescent gynecomastia Endocrinology Diabetes and Metabolism 030209 endocrinology & metabolism lcsh:Diseases of the endocrine glands. Clinical endocrinology Impaired glucose tolerance 03 medical and health sciences 0302 clinical medicine Endocrinology Hypergonadotropic hypogonadism dysglycemia Hypogonadotropic hypogonadism Diabetes mellitus Internal medicine Breast enlargement medicine 030212 general & internal medicine lcsh:RC799-869 skin and connective tissue diseases Breast development lcsh:RC648-665 business.industry medicine.disease Impaired fasting glucose Gynecomastia diabetes mellitus Original Article lcsh:Diseases of the digestive system. Gastroenterology business |
| Zdroj: | Indian Journal of Endocrinology and Metabolism, Vol 21, Iss 1, Pp 160-164 (2017) Indian Journal of Endocrinology and Metabolism |
| ISSN: | 2230-8210 |
| Popis: | Background: Gynecomastia during adolescence is common though etiology is not clear. We studied the clinical and hormonal profile of adolescent patients with gynecomastia. Methodology: Patients who had onset of breast development between age 10 and 20 years were included in this study. Their clinical profile, biochemical, and hormonal parameters were studied. Results: Of 94 patients with gynecomastia, 4 had hypogonadotropic hypogonadism, 4 had hypergonadotropic hypogonadism, and 1 had fibroadenosis, but in majority (90.4%), no apparent cause for breast enlargement was evident. In the idiopathic group, majority were obese (63%). Fourteen (16%) patients had impaired fasting glucose or impaired glucose tolerance. Another twenty patients had subtle abnormalities (high 1 h glucose or glucose peak at 2 h). Twenty-nine percent of lean and 38% of obese patients had mild abnormalities in glucose profile. Sixty percent of patients had family background of diabetes. Obese patients had lower testosterone as compared to lean patients; however, estradiol, luteinizing hormone, and follicle-stimulating hormone levels were similar in the two groups. Conclusion: Gynecomastia during adolescence is associated with obesity, dysglycemia, and family background of diabetes mellitus. |
| Databáze: | OpenAIRE |
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