Pre-operative risk assessment and risk reduction before surgery
Autor: | Don Poldermans, Sanne E. Hoeks, Harm H.H. Feringa |
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Přispěvatelé: | Anesthesiology |
Rok vydání: | 2008 |
Předmět: |
medicine.medical_specialty
Myocardial Infarction Culprit Preoperative care Risk Assessment Patient Care Planning Postoperative Complications Internal medicine Preoperative Care medicine Humans Myocardial infarction Risk factor Thrombus Aspirin business.industry Perioperative medicine.disease Surgery Surgical Procedures Operative Cardiology Cardiology and Cardiovascular Medicine business Risk assessment Risk Reduction Behavior medicine.drug |
Zdroj: | Journal of the American College of Cardiology, 51(20), 1913-1924. Elsevier Inc. |
ISSN: | 0735-1097 |
Popis: | Perioperative myocardial infarctions are the predominant cause of morbidity and mortality in patients undergoing noncardiac surgery. The pathophysiology of perioperative myocardial infarction is complex. Prolonged myocardial ischemia due to the stress of surgery in the presence of a hemodynamically significant coronary lesion, leading to subendocardial ischemia, and acute coronary artery occlusion after plaque rupture and thrombus formation contribute equally to these devastating events. Perioperative management aims at optimizing the patient's condition by identification and modification of underlying cardiac risk factors and diseases. During recent decades there has been a shift from the assessment and treatment of the underlying culprit coronary lesion toward a systemic medical therapy aiming at prevention of myocardial oxygen supply demand mismatch and coronary plaque stabilization. Beta-blockers, statins, and aspirin are widely used in this setting. The role of prophylactic coronary revascularization has been restricted to the same indications as the nonoperative setting. Therefore pre-operative cardiac testing is recommended only if test results will change perioperative management. In addition to the limited perioperative period, physicians should benefit from this opportunity to initiate lifestyle changes and medical therapy to lessen the impact of cardiac risk factors, as patients should live long enough after the operation to enjoy the benefits of surgery. |
Databáze: | OpenAIRE |
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