Iodine(III)-Mediated Electrochemical Trifluoroethoxylactonisation: Rational Reaction Optimisation and Prediction of Mediator Activity

Autor:	Emre Babaoglu, Gerhard Hilt, Robert Möckel
Rok vydání:	2018
Předmět:	Reaction conditions 010405 organic chemistry Design of experiments Organic Chemistry chemistry.chemical_element General Chemistry 010402 general chemistry Iodine Electrochemistry 01 natural sciences Combinatorial chemistry Catalysis 0104 chemical sciences chemistry
Zdroj:	Chemistry (Weinheim an der Bergstrasse, Germany). 24(59)
ISSN:	1521-3765
Popis:	A new electrochemical iodine(III)-mediated cyclisation reaction for the synthesis of 4-(2,2,2-trifluoroethoxy)isochroman-1-ones is presented. Based on this reaction design of experiments and multivariate linear regression analysis were used to demonstrate their first application in an electrochemical reaction. The broad applicability of these reaction conditions could be shown by a range of substrates and an extensive compatibility test.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b475434d4393da0cf780a07023fd02bb https://pubmed.ncbi.nlm.nih.gov/30133017 Zobrazit plný text záznamu Plný text ve formátu PDF