| Autor: |
Clodia Osipo, Kathy S. Albain, Andrew K. Dingwall, Jeffrey Ng, Ali Piracha, Andrei Zlobin, Debra Wyatt, Daniel S. Peiffer |
| Rok vydání: |
2023 |
| DOI: |
10.1158/0008-5472.22422101 |
| Popis: |
Figure S1: Individual DAXX siRNA sequences have similar effect on DAXX expression and TIC-survival. Figure S2: DAXX status has little effect on bulk cell proliferation. Figure S3: Survival curves of each cell dilution from ELDA. Figure S4: Kaplan-Meier RFS Outcomes. Figure S5: Kaplan-Meier RFS Outcomes based on Nodal status. Figure S6: Global changes in gene expression due to DAXX depletion. Figure S7: Sites of DAXX enrichment and resulting changes in EMT following DAXX knockdown. Figure S8: DNA methylation or DNMT1 is required for restriction of TIC-survival and gene expression. Figure S9: DAXX requires DNMT1 to restrict TIC-associated gene expression and representative bisulfite sequencing results. Figure S10: DAXX overexpression has little effect on bulk cell proliferation, but is sufficient to inhibit NOTCH signaling. Figure S11: DAXX is sufficient to increase luminal/epithelial genes and inhibit EMT genes under ET conditions. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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