Primary Biliary Cirrhosis
| Autor: | Ernesto Molmenti, Ken L. Ford, Karl A. Glastad, David M. Watkins, Jeffrey Scott Wenzel, Amanda L. Donohoe |
|---|---|
| Rok vydání: | 2001 |
| Předmět: |
medicine.medical_specialty
Carcinoma Hepatocellular Cirrhosis Biliary cirrhosis Gastroenterology 030218 nuclear medicine & medical imaging 03 medical and health sciences 0302 clinical medicine Primary biliary cirrhosis Radiologic sign Internal medicine Hypertension Portal Ascites medicine Humans Radiology Nuclear Medicine and imaging Halo sign Retrospective Studies Liver Cirrhosis Biliary Portal Vein business.industry Liver Neoplasms Thrombosis General Medicine medicine.disease Magnetic Resonance Imaging Liver Regeneration Liver Transplantation 3. Good health Portal vein thrombosis 030220 oncology & carcinogenesis Splenomegaly Portal hypertension Lymph Nodes Radiology medicine.symptom business |
| Zdroj: | American Journal of Roentgenology. 176:885-889 |
| ISSN: | 1546-3141 0361-803X |
| Popis: | This study reviews the prevalence of MR imaging abnormalities seen in 21 consecutive patients with primary biliary cirrhosis before transplantation and describes a new MR imaging sign in these patients: the MR imaging periportal halo sign.Abdominal adenopathy was present in 62% of the patient population, and none of the patients with adenopathy had a known malignancy. Findings associated with end-stage cirrhosis and portal hypertension were seen and included ascites (62%), splenomegaly (71%), portosystemic collaterals (57%), portal vein thrombosis (5%), and hepatocellular carcinoma (5%). The MR imaging periportal halo sign was seen in 43% of patients with primary biliary cirrhosis, but none of the patients in a sex- and age-matched cohort of 21 patients with cirrhosis not caused by primary biliary cirrhosis had the finding. Statistical analysis of these results produced a t score of 3.97 and a p value of less than 0.001, suggesting that this new MR imaging sign is highly specific for the diagnosis of primary biliary cirrhosis. |
| Databáze: | OpenAIRE |
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