Rates of malignancy in incidentally discovered thyroid nodules evaluated with sonography and fine-needle aspiration
| Autor: | David H. Slavit, Karen Fried, Arnold Komisar, Andrew G. Sikora, Amy Liebeskind |
|---|---|
| Rok vydání: | 2005 |
| Předmět: |
Thyroid nodules
Male medicine.medical_specialty Biopsy Fine-Needle medicine.disease_cause Malignancy Diagnosis Differential Predictive Value of Tests Biopsy medicine Humans Radiology Nuclear Medicine and imaging Thyroid Neoplasms Thyroid Nodule Thyroid neoplasm Retrospective Studies Ultrasonography Radiological and Ultrasound Technology medicine.diagnostic_test business.industry Thyroid disease Thyroid Nodule (medicine) Middle Aged medicine.disease Magnetic Resonance Imaging Carcinoma Papillary Fine-needle aspiration medicine.anatomical_structure Carcinoma Medullary Female Radiology medicine.symptom business Nuclear medicine Tomography X-Ray Computed |
| Zdroj: | Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine. 24(5) |
| ISSN: | 0278-4297 |
| Popis: | Objective. The purpose of this study was to compare the rate of malignancy in thyroid nodules discovered incidentally on magnetic resonance imaging, computed tomography, and sonography with the rate of malignancy in nonincidentally discovered nodules. Methods. All thyroid sonographic and fine-needle aspiration (FNA) procedures performed during a 6-month period were retrospectively reviewed. Study indications were categorized as incidental (thyroid nodules found on magnetic resonance imaging, computed tomography, or sonography performed for nonthyroid indications) or nonincidental (studies prompted by abnormal physical examination findings or laboratory values or signs or symptoms suggestive of thyroid disease). Rates of malignancy in patients with incidentally discovered nodules were compared with rates in patients with nonincidental thyroid abnormalities by the Fisher exact test. Results. Of 225 thyroid sonographic studies, 35 (16%) were performed for incidentally discovered thyroid nodules, and 190 (84%) were performed for evaluation of nonincidental thyroid abnormalities. A total of 21 patients (60%) in the incidental group and 90 patients (47%) in the nonincidental group underwent FNA. The rate of malignancy in nodules examined by biopsy in the incidental group was 17% compared with 3% in the nonincidental group (P = .020). Patient sex, multiplicity of nodules, nodule size, echo texture, and presence of calcifications did not differ significantly between the groups. The mean age of patients in the incidental group was significantly higher (61 versus 51 years; P = .007); however, advanced age was not associated with a greater rate of malignancy. Conclusions. This study identified an unexpectedly high rate of malignancy in incidentally discovered thyroid nodules, suggesting that incidentally discovered thyroid nodules should be evaluated with follow-up thyroid sonography and FNA. |
| Databáze: | OpenAIRE |
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