Assessment of the nevirapine safety signal using data from the national antiretroviral dispensing database: a retrospective study
| Autor: | Assegid Mengistu, Johannes Gaeseb, Francis Kalemeera |
|---|---|
| Rok vydání: | 2015 |
| Předmět: |
0301 basic medicine
Nevirapine Pharmacy computer.software_genre 03 medical and health sciences immune system diseases Pharmacovigilance Medicine Adverse effect Skin Grade IV Signal Database Grade III business.industry Health Policy Research virus diseases Retrospective cohort study Odds ratio Proportional reaction ratio Adverse reaction 030112 virology Confidence interval Clinical trial Liver Christian ministry Reaction ratio business computer medicine.drug |
| Zdroj: | Journal of Pharmaceutical Policy and Practice |
| ISSN: | 2052-3211 |
| Popis: | Background Clinical trials showed a higher risk of skin- and liver- related adverse reactions when NVP-based antiretroviral therapy (ART) was initiated in female and male patients with baseline CD4 cell counts ≥250 and ≥400, respectively. Some studies reported no difference in risk between the high and low CD4 count groups. Consequently, the use of NVP-based ART in all patients with a CD4 cell count |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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