Effects of low-dose oxygen administration on renal blood oxygenation level-dependent MRI in children with glomerulonephritis

Autor: Sayaka Ono, Masakazu Mimaki, Kazuhiro Takahashi, Tomohiko Nishino
Rok vydání: 2021
Předmět:
Zdroj: Magma (New York, N.Y.). 34(6)
ISSN: 1352-8661
Popis: Children are often sedated for renal blood oxygenation level-dependent (BOLD) magnetic resonance imaging (MRI) and may require low-dose oxygen administration. It is unclear whether low-dose oxygen administration affects results of BOLD MRI. We investigated the effect of low-dose oxygen administration on renal BOLD MRI and its variation by the presence or absence of renal disease. We retrospectively examined children undergoing MRI for renal disease between 2013 and 2020. Patients were divided into glomerulonephritis and non-glomerulonephritis groups; spin relaxation time (T2*) was determined using a 3.0 T MRI system. The study included 10 children (5 patients in each group); patient characteristics between the groups did not differ significantly. In the entire cohort, oxygen administration reduced mean spin relaxation rate (R2*) value in the medulla (p
Databáze: OpenAIRE