A study of the radioprotective effect of vasopressin induced ischaemia on the small intestine of the dog and its relation to circulatory parameters
| Autor: | Stig Borgström, Göran Nylander, Karl Fredrik Aronsen, Clas Lindström, Peter Dougan, Lars Jacobsson |
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| Rok vydání: | 1982 |
| Předmět: |
medicine.medical_specialty
Vasopressin Vasopressins Ischemia Radiation-Protective Agents Body weight Microcirculation Dogs Intestinal mucosa medicine.artery Internal medicine Intestine Small medicine Animals Radiology Nuclear Medicine and imaging Superior mesenteric artery Intestinal Mucosa Chemistry General Medicine medicine.disease Small intestine Radiation Injuries Experimental medicine.anatomical_structure Endocrinology Regional Blood Flow Circulatory system |
| Zdroj: | The British Journal of Radiology. 55:568-573 |
| ISSN: | 1748-880X 0007-1285 |
| Popis: | The degrees of radioprotection achievable by clamping mesenteric vessels, blocking microcirculation by degradable micro-spheres and various doses of vasopressin injected into the superior mesenteric artery in dogs have been studied using a technique in which series of localized irradiations of segments of the small intestine were made. The flow speeds of blood in the small intestine and through the intestinal mucosa were examined by an isotope technique using a mixture of 99TcmSn colloid and 32P. Vasopressin has been observed to influence the mucosal circulation. Of the alternatives tested, vasopressin at a dosage of 0.05 IU/kg body weight resulted in the highest degree of radioprotection of the small intestine of the dog. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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