Protected Chloroethyl and Chloropropyl Amines as Conformationally Unrestricted Annulating Reagents

Autor:	Purnima Khandelwal, John Hynes, Hyunsoo Park, David Marcoux, Michael Galella, T. G. Murali Dhar, Qing Shi, Mariah C. Meehan
Rok vydání:	2017
Předmět:	Annulation Scope (project management) 010405 organic chemistry Chemistry Reagent Organic Chemistry Physical and Theoretical Chemistry 010402 general chemistry 01 natural sciences Biochemistry Combinatorial chemistry 0104 chemical sciences
Zdroj:	Organic Letters. 20:337-340
ISSN:	1523-7052 1523-7060
DOI:	10.1021/acs.orglett.7b03548
Popis:	The purpose of this letter is to document the use of protected chloroethyl and chloropropyl amines as conformationally unrestricted ambiphilic reagents that undergo annulation reactions with Michael acceptors. This reaction is wide in scope and utilizes reagents that are commercially available, inexpensive, and stable. Furthermore, this reaction is easy to execute and proceeds rapidly.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b45d4112dd032272d7214f8907154e08 https://doi.org/10.1021/acs.orglett.7b03548 Zobrazit plný text záznamu