Enteropathic arthritis in Brazil: data from the Brazilian registry of spondyloarthritis
| Autor: | Gustavo G, Resende, Cristina C D, Lanna, Adriana B, Bortoluzzo, Célio R, Gonçalves, José Antonio Braga, da Silva, Antonio Carlos, Ximenes, Manoel B, Bértolo, Sandra L E, Ribeiro, Mauro, Keiserman, Rita, Menin, Thelma L, Skare, Sueli, Carneiro, Valderílio F, Azevedo, Walber P, Vieira, Elisa N, Albuquerque, Washington A, Bianchi, Rubens, Bonfiglioli, Cristiano, Campanholo, Hellen M S, Carvalho, Izaias P, Costa, Angela P, Duarte, Charles L, Kohem, Nocy, Leite, Sonia A L, Lima, Eduardo S, Meirelles, Ivânio A, Pereira, Marcelo M, Pinheiro, Elizandra, Polito, Francisco Airton C, Rocha, Mittermayer B, Santiago, Maria de Fátima L C, Sauma, Valeria, Valim, Percival D, Sampaio-Barros |
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| Jazyk: | angličtina |
| Předmět: |
Adult
Male Ulcerative rectocolitis Estudos de registro Doença de Crohn Arthritis Enteropathic arthritis Crohn's Disease Middle Aged Retocolite ulcerativa Crohn Disease Registry studies Spondylarthritis Humans General Earth and Planetary Sciences Colitis Ulcerative Female Prospective Studies Registries Brazil Artrite enteropática General Environmental Science |
| Zdroj: | Revista Brasileira de Reumatologia (English Edition). (6):452-459 |
| ISSN: | 2255-5021 |
| DOI: | 10.1016/j.rbre.2013.04.001 |
| Popis: | Inflammatory bowel diseases (Crohn's disease and ulcerative rectocolitis) have extraint- estinal manifestations 25% of the patients, with the most common one being the entero- pathic arthritis.MethodsProspective, observational, multicenter study with patients from 29 reference cen- ters participating in the Brazilian Registry of Spondyloarthritis (RBE), which incorporates the RESPONDIA (Ibero-American Registry of Spondyloarthritis) group. Demographic and clinical data were collected from 1472 patients and standardized questionnaires for the as- sessment of axial mobility, quality of life, enthesitic involvement, disease activity and func- tional capacity were applied. Laboratory and radiographic examinations were performed. The aim of this study is to compare the clinical, epidemiological, genetic, imaging, treat- ment and prognosis characteristics of patients with enteropathic arthritis with other types of spondyloarthritis in a large Brazilian cohort.ResultsA total of 3.2% of patients were classified as having enteroarthritis, 2.5% had spon- dylitis and 0.7%, arthritis (peripheral predominance). The subgroup of individuals with en- teroarthritis had a higher prevalence in women (P < 0.001), lower incidence of inflammatory axial pain (P < 0.001) and enthesitis (P = 0.004). HLA-B27 was less frequent in the group with enteroarthritis (P = 0.001), even when considering only those with the pure axial form. There was a lower prevalence of radiographic sacroiliitis (P = 0.009) and lower radiographic score (BASRI) (P = 0.006) when compared to patients with other types of spondyloarthritis. They also used more corticosteroids (P < 0.001) and sulfasalazine (P < 0.001) and less non- steroidal anti-inflammatory drugs (P < 0.001) and methotrexate (P = 0.001).ConclusionThere were differences between patients with enteroarthritis and other types of spondyloarthritis, especially higher prevalence of females, lower frequency of HLA-B27, associated with less severe axial involvement. |
| Databáze: | OpenAIRE |
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