Coronavirus-associated kidney outcomes in COVID-19, SARS, and MERS: a meta-analysis and systematic review

Autor: Albert C.M. Ong, Shoulian Zhou, Bo Yang, Cheng Xue, Jing Xu, Zhiguo Mao
Rok vydání: 2020
Předmět:
Zdroj: Renal Failure
article-version (VoR) Version of Record
Renal Failure, Vol 43, Iss 1, Pp 1-15 (2021)
ISSN: 1525-6049
0886-022X
DOI: 10.1080/0886022x.2020.1847724
Popis: Objectives\ud \ud A meta-analysis and systematic review was conducted on kidney-related outcomes of three recent pandemics: SARS, MERS, and COVID-19, which were associated with potentially fatal acute respiratory distress syndrome (ARDS).\ud \ud \ud Methods\ud \ud A search of all published studies until 16 June 2020 was performed. The incidence/prevalence and mortality risk of acute and chronic renal events were evaluated, virus prevalence, and mortality in preexisting hemodialysis patients was investigated.\ud \ud \ud Results\ud \ud A total of 58 eligible studies involving 13452 hospitalized patients with three types of coronavirus infection were included. The reported incidence of new-onset acute kidney injury (AKI) was 12.5% (95% CI: 7.6%–18.3%). AKI significantly increased the mortality risk (OR = 5.75, 95% CI 3.75–8.77, p
Databáze: OpenAIRE