When a Desquamating Rash Leads to a Challenging Diagnosis: Differential diagnosis of a desquamating rash

Autor: Almeida, Sara Isabel De, Briosa, Filipa, Rios, Joana, Oom, Paulo
Jazyk: angličtina
Rok vydání: 2021
Zdroj: Portuguese Journal of Pediatrics; Vol. 52 No. 3 (2021)
Portuguese Journal of Pediatrics; Vol. 52 N.º 3 (2021)
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Agência para a Sociedade do Conhecimento (UMIC)-FCT-Sociedade da Informação
instacron:RCAAP
ISSN: 2184-4453
2184-3333
Popis: A desquamating rash may pose a true clinical challenge. Therefore, history and clinical course are crucial to do an accurate diagnosis. We present a case of a 17 year-old boy submitted to a pilonidalis sinus excision, who presented to the emergency department with erythema and desquamation of lips, a scarlatiniform rash, an extensive desquamation of hands and feet and infection of the surgical site. Given the suspicion of a staphylococcal scalded skin syndrome intravenous antibiotics were immediately started. During day sixth of admission a sudden itching erythematous and desquamative rash appeared on the face and body, which was worse after administration of cefuroxime. This antibiotic was stopped and it was noticed a clinical improvement. Skin biopsy revealed toxiderma. At follow-up a positive oral provocation test for cefuroxime confirmed the cause of toxiderma. This case brings out to discussion the importance of clinical course to make the correct diagnosis.
Portuguese Journal of Pediatrics, Vol. 52 No. 3 (2021)
Databáze: OpenAIRE