Association Between Geriatric Nutritional Risk Index and Frailty in Older Hospitalized Patients
| Autor: | Meng Zhang, Xiaoyu Shu, Lisha Hou, Chenkai Wu, Langli Gao, Xuchao Peng, Jirong Yue, Taiping Lin, Yanli Zhao, Dongmei Xie |
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| Rok vydání: | 2021 |
| Předmět: |
Male
medicine.medical_specialty China Nutritional Status Comorbidity Severity of Illness Index older people Sex Factors Internal medicine Nutritional risk index medicine Prevalence Humans Geriatric Assessment Depression (differential diagnoses) Aged Original Research Polypharmacy Aged 80 and over Receiver operating characteristic Frailty business.industry Malnutrition Area under the curve Age Factors General Medicine medicine.disease Hospitalization Cross-Sectional Studies Nutrition Assessment ROC Curve Clinical Interventions in Aging Female Ordered logit Geriatrics and Gerontology Geriatric Nutritional Risk Index business |
| Zdroj: | Clinical Interventions in Aging |
| ISSN: | 1178-1998 |
| Popis: | Yanli Zhao, 1 Taiping Lin, 1 Lisha Hou, 1 Meng Zhang, 1 Xuchao Peng, 1 Dongmei Xie, 1 Langli Gao, 1 Xiaoyu Shu, 1 Jirong Yue, 1 Chenkai Wu 2 1Department of Geriatrics and National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, Chengdu, Sichuan, 610041, People’s Republic of China; 2Global Health Research Center, Duke Kunshan University, Kunshan, 215300, Jiangsu, People’s Republic of ChinaCorrespondence: Jirong YueDepartment of Geriatrics and National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, Chengdu, Sichuan Province, 610041, People’s Republic of ChinaTel +86 18980601143Email yuejirong11@hotmail.comObjective: Previous studies have explored the association between malnutrition and frailty, but no study has investigated whether the Geriatric Nutritional Risk Index (GNRI), a simple and objective nutritional risk screening tool, is associated with the frailty of older adults. The study aimed to examine the relationship between nutrition-related risk, as assessed by the GNRI, and frailty among older hospitalized patients.Methods: A cross-sectional study was conducted in the West China Hospital of Sichuan University with 740 patients aged ≥ 70 years between March 2016 and Jan 2017. Nutritional and frailty status was evaluated with the GNRI and FRAIL scale, respectively. The adjusted and unadjusted ordinal logistic regression analyses were used to examine the relationship between nutritional risk and frailty. The ability of GNRI in detecting frailty was assessed by receiver operating characteristic (ROC) curve analysis.Results: The prevalence of low, moderate, and severe nutritional risk among frail patients were 30.1%, 27.6%, and 12.5%, respectively. Ordinal logistic regression analysis showed that malnutrition assessed by the GNRI had a significant association with frailty after adjustment of age, sex, polypharmacy, comorbidity, vision impairment, hearing impairment, cognitive impairment, and depression. In the ROC analysis, the area under the curve for GNRI identifying frailty was 0.698 (95% CI: 0.66– 0.74; P< 0.001), and the optimal cut-point value was 97.16 (sensitivity: 64.3%; specificity: 66.9%).Conclusion: Nutrition-related risk screened by the GNRI was independently associated with frailty. The GNRI could be used as a simple tool in detecting nutritional risk and frailty status of older patients.Keywords: frailty, malnutrition, Geriatric Nutritional Risk Index, older people |
| Databáze: | OpenAIRE |
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