Nematicidal activity of oleanolic acid derivatives on Meloidogyne incognita
| Autor: | Nabila Hassan, Shahina Fayyaz, Erum Iqbal, Zarina Bano, Zareena Kiran, Sara Sara, Bina S. Siddiqui, Anjum Ayub, Sabira Begum |
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| Rok vydání: | 2020 |
| Předmět: |
biology
010405 organic chemistry Stereochemistry Organic Chemistry Plant Science Carbon-13 NMR biology.organism_classification 01 natural sciences Biochemistry 0104 chemical sciences Analytical Chemistry 010404 medicinal & biomolecular chemistry chemistry.chemical_compound Nematode chemistry Meloidogyne incognita Proton NMR Oleanolic acid |
| Zdroj: | Natural Product Research. 35:5138-5144 |
| ISSN: | 1478-6427 1478-6419 |
| DOI: | 10.1080/14786419.2020.1786826 |
| Popis: | In this study, oleanolic acid and its derivatives were studied for their invivo nematicidal activity against root-knot nematode (RKN) Meloidogyne incognita. A series of C-28-oleanolates including five new (5, 7–10) and seven known (1–4, 6, 11, 12) compounds were synthesised and their nematicidal activity was determined and compared with the standard nematicide furadan for the first time. The structures of the compounds were elucidated through 1H NMR, 13C NMR and EIMS. Compounds 4, 5, 7, 8 and 10 showed ∼ 90% inhibition of RKN at 0.125% concentration after 72 h showing their potential use in nematicidal control. |
| Databáze: | OpenAIRE |
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