Acrylate yellow filters in operating lights protect against photosensitization tissue damage
| Autor: | J.H.P. Wilson, F W M de Rooij, Peter D. Siersema, P. Hinnen, H. W. Tilanus, G. Voortman |
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| Přispěvatelé: | Internal Medicine, Surgery |
| Rok vydání: | 2000 |
| Předmět: |
Acrylate polymer
medicine.medical_specialty Time Factors Swine medicine.medical_treatment Photodynamic therapy Hepatic carcinoma medicine.disease_cause Photochemistry Necrosis chemistry.chemical_compound Photosensitivity Tissue damage medicine Animals Humans Photosensitivity Disorders Cells Cultured Lighting Acrylate Intraoperative Care business.industry Protective Devices Fluorescence Surgery Acrylates Photochemotherapy chemistry business Filtration Ultraviolet |
| Zdroj: | British Journal of Surgery, 87, 231-235. John Wiley & Sons Ltd. |
| ISSN: | 0007-1323 |
| DOI: | 10.1046/j.1365-2168.2000.01325.x |
| Popis: | Background Photosensitized patients are exposed to bright lights when undergoing intraoperative photodynamic therapy or fluorescence measurements. Acrylate yellow filters might reduce unwanted tissue damage. Methods To investigate the protective value of these filters, the spectral power distribution of the operating lights and light energy densities with and without an acrylate yellow filter were measured. Subsequently the effects of light exposure on the survival of a human hepatocellular carcinoma cell line and the photodamage induced in pig tissues after the administration of 5-aminolaevulinic acid were also studied. Results The light energy density in the ultraviolet and blue region of the light spectrum emitted by the operating light was reduced up to 50 per cent by the acrylate yellow filter. The survival of photosensitized cells was longer and photodamage induced in pig tissues was less when exposed to filtered light. Conclusion Photodamage induced by operating lights can be reduced by filtering out ultraviolet and blue light by means of acrylate yellow filters. |
| Databáze: | OpenAIRE |
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