Magnetic resonance angiography, function and viability evaluation in patients with Kawasaki disease
Autor: | Sophie Mavrogeni, Ioannis Seimenis, Xenofon Krikos, George Papadopoulos, Marouso Douskou, Aglaia Giannoulia, Dennis V. Cokkinos, Savas Kaklis, Evangelos Karanasios, George Varlamis |
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Rok vydání: | 2006 |
Předmět: |
Gadolinium DTPA
Male medicine.medical_specialty Population Myocardial Infarction Contrast Media Mucocutaneous Lymph Node Syndrome Magnetic resonance angiography medicine Image Processing Computer-Assisted Humans Radiology Nuclear Medicine and imaging cardiovascular diseases education Child Ultrasonography education.field_of_study Radiological and Ultrasound Technology medicine.diagnostic_test business.industry Coronary Aneurysm Magnetic resonance imaging Steady-state free precession imaging Gold standard (test) medicine.disease Coronary arteries medicine.anatomical_structure cardiovascular system Kawasaki disease Female Radiology Myocardial infarction diagnosis Cardiology and Cardiovascular Medicine business Magnetic Resonance Angiography |
Zdroj: | Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance. 8(3) |
ISSN: | 1097-6647 |
Popis: | We evaluated the ability of magnetic resonance imaging to perform a noninvasive assessment of coronary arteries, function and viability in one examination in a population with Kawasaki disease.Magnetic resonance angiography (MRA) can identify coronary abnormalities in patients with Kawasaki disease (KD). Contrast enhanced cardiovascular magnetic resonance (CeCMR) is the current gold standard for scar detection. Steady-state, free precession (SSFP) cine is a reliable technique to evaluate myocardial function and wall motion.Twenty patients with KD aged 7-12 yrs, were examined. Coronary MRA was performed using a 1.5 T system with two ECG-triggered pulse sequences. CeCMR images were acquired 15 minutes after the i.v. injection of 0.1 mmol/kg Gd-DTPA using an inversion recovery sequence. SSFP cines were acquired using 6-mm short-axis slices from the atrioventricular ring to the apex.Aneurysms of the coronary arteries were identified in 7 patients and coronary ectasia was present in the remaining 12 patients while 1 patient had both. Transmural anterior-apical scar was detected by ceCMR in two cases, while small inferior necrosis was identified in another 2 cases. Left ventricular function was deteriorated only in the two patients with antero-apical infarction. The presence of myocardial infarction was detected in the territory supplied by the involved coronary artery.In Kawasaki disease MRA, SSFP cine and ceCMR are able to perform noninvasive coronary artery evaluation, function and infarct detection in a single study. |
Databáze: | OpenAIRE |
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