Determination of Zy 17617B in plasma by solid-phase extraction and liquid chromatography with automated pre-column exchange
| Autor: | Daniel F. Chollet, M. Salanon |
|---|---|
| Rok vydání: | 1992 |
| Předmět: |
Chromatography
Chemistry Elution Organic Chemistry Extraction (chemistry) Analytical chemistry Reproducibility of Results General Medicine Plasma Biochemistry Biological fluid Analytical Chemistry Spectrometry Fluorescence Human plasma Humans Benzimidazoles Solid phase extraction Sample extraction Antidiarrheals Column (data store) Chromatography Liquid |
| Zdroj: | Journal of Chromatography A. 593:73-78 |
| ISSN: | 0021-9673 |
| DOI: | 10.1016/0021-9673(92)80269-z |
| Popis: | An automated chromatographic system, combining solid-phase extraction and automated pre-column exchange, is described for the routine determination of Zy 17617B at the pmol/ml level in human plasma. The sample extraction and elution onto the analytical column were performed automatically and concomitantly using a conventional liquid chromatographic apparatus equipped with a Merck OSP-2 on-line sample preparator. Validation data demonstrate the reliability of the method. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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