Plasma Levels of B-Type Natriuretic Peptide in Patients With Unstable Angina Pectoris or Acute Myocardial Infarction: Prognostic Significance and Therapeutic Implications

Autor: Waqas Ahmed, Martin A. Alpert, Naveed Ahktar, Mumtaz Ali Shah, Ali Yawar Alam, Saman Zafar
Rok vydání: 2007
Předmět:
Adult
Male
medicine.medical_specialty
Time Factors
medicine.drug_class
medicine.medical_treatment
Cardiac Output
Low
Myocardial Infarction
Myocardial Ischemia
030204 cardiovascular system & hematology
Coronary Angiography
Revascularization
Risk Assessment
Angina
03 medical and health sciences
0302 clinical medicine
Troponin T
Predictive Value of Tests
Recurrence
Internal medicine
Natriuretic Peptide
Brain
medicine
Natriuretic peptide
Humans
Angina
Unstable
Prospective Studies
cardiovascular diseases
030212 general & internal medicine
Myocardial infarction
Angioplasty
Balloon
Coronary
Coronary Artery Bypass
Aged
Unstable angina
business.industry
Incidence
Middle Aged
medicine.disease
Treatment Outcome
Heart failure
Cardiology
Myocardial infarction complications
Female
Myocardial infarction diagnosis
Cardiology and Cardiovascular Medicine
business
Biomarkers
hormones
hormone substitutes
and hormone antagonists
Zdroj: Angiology. 58:269-274
ISSN: 1940-1574
0003-3197
DOI: 10.1177/0003319707302543
Popis: Plasma B-type natriuretic peptide (BNP) levels were obtained from 146 patients with unstable angina pectoris, non—ST-segment elevation myocardial infarction (MI), or ST-segment elevation MI to determine their value in predicting the presence of new heart failure, recurrent MI or ischemia, or death 1 month after the index event. Patients with elevated plasma BNP levels (>80 pg/mL) had a significantly higher incidence of new heart failure and all-cause mortality than those with a normal plasma BNP level (≤80 pg/mL). Early revascularization with percutaneous intervention or coronary artery bypass grafting significantly reduced the incidence of new heart failure and all-cause mortality in patients with an elevated plasma BNP level, but had no effect on individual outcomes in the normal plasma BNP subgroup.
Databáze: OpenAIRE
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