Comparison of Carotid Atherosclerosis between Patients at High Altitude and Sea Level: A Chinese Atherosclerosis Risk Evaluation Study
| Autor: | Gador M Canto, Xihai Zhao, Yuntai Cao, Lina Yue, Chun Yuan, Haihua Bao, Yousen Wu, Honglu Shi, Yan Song, Rui Li, Guangbin Wang, Hiroko Watase, Daniel S. Hippe, Hongqian Zhang |
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| Rok vydání: | 2019 |
| Předmět: |
Carotid atherosclerosis
Carotid Artery Diseases Male China Carotid arteries Lumen (anatomy) Risk Assessment Severity of Illness Index 03 medical and health sciences 0302 clinical medicine Altitude Predictive Value of Tests Risk Factors medicine Humans Vascular Calcification Sea level Aged medicine.diagnostic_test business.industry Rehabilitation Magnetic resonance imaging Effects of high altitude on humans Middle Aged Plaque Atherosclerotic Risk evaluation Carotid Arteries Cross-Sectional Studies Surgery Female Neurology (clinical) Cardiology and Cardiovascular Medicine Nuclear medicine business 030217 neurology & neurosurgery Magnetic Resonance Angiography |
| Zdroj: | Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association. 29(2) |
| ISSN: | 1532-8511 |
| Popis: | Objectives: To investigate the differences in characteristics of carotid plaques between patients Xining at high altitude and Jinan at sea level using magnetic resonance (MR) imaging. Methods: Subjects were recruited from a cross-sectional, observational, multicenter imaging study of CARE-II study. Forty-nine (mean age 63.3 ± 12.0 years, 33 males) and 51 (mean age 64.5 ± 12.0 years, 34 males) patients were recruited from a site located in a high altitude region and a site located near sea level, respectively. All patients underwent multicontrast MR vessel wall imaging for carotid arteries on 3.0 T MR scanner. The carotid plaques features were compared between 2 patient groups. Results: Compared with patients at sea level, those at high altitude had significantly greater lumen area (58.5 ± 17.8 mm2 versus 50.0 ± 19.6 mm2, P = .008), smaller maximum normalized wall index (48.6% ± 14.2% versus 57.8% ± 16.3%, P = .002), and smaller percentage volume of calcium (0.9% versus 5.6%, P |
| Databáze: | OpenAIRE |
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