Centrifugal blood pump with a hydraulically-levitated impeller for a permanently implantable biventricular assist device
| Autor: | Shinichi Tsujimura, Kuniyoshi Watanabe, Daniel Oestmann, Seiichi Ito, Seiji Ichikawa, Julia Glueck, Atsushi Hata, Yukihiko Nosé, Toshiyuki Shinohara, Toshimasa Asai, Tadashi Motomura |
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| Rok vydání: | 2004 |
| Předmět: |
Materials science
Biventricular assist device Pulsatile flow Biomedical Engineering Medicine (miscellaneous) Bioengineering Sensitivity and Specificity Flow measurement law.invention Biomaterials Impeller Implants Experimental law Materials Testing medicine Animals Heart-Assist Devices Thrombus Bearing (mechanical) Equipment Safety Hemodynamics General Medicine Equipment Design Centrifugal pump medicine.disease Pulsatile Flow Models Animal Cattle Biomedical engineering |
| Zdroj: | Artificial organs. 28(6) |
| ISSN: | 0160-564X |
| Popis: | A permanently implantable biventricular assist device (BVAD) system has been developed with a centrifugal pump which is activated by a hydraulically-levitated impeller. The pump impeller floats hydraulically into the top contact position; this position prevents thrombus formation by creating a washout effect at the bottom bearing area, a common stagnant region. The pump was subjected to in vitro studies using a pulsatile mock circulation loop to confirm the impeller's top contact position and the swinging motion produced by the pulsation. Eleven in vivo BVAD studies confirmed that this swinging motion eliminated blood clot formation. Twenty-one pumps im-planted for up to three months did not reveal any thrombosis in the pumps or downstream organs. One exception was a right pump which was exposed to severe low flow due to the kinking of the outflow graft by the accidental pulling of the flow meter cable. Three ninety-day BVAD studies were achieved without thrombus formation. |
| Databáze: | OpenAIRE |
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