Role of contrast-enhanced ultrasound to define prognosis and predict response to biotherapy in pancreatic neuroendocrine tumors
| Autor: | A. Giorgio, Antonio C. Bianco, Maurizio Gasperi, Antongiulio Faggiano, A. Di Sarno, A. Colao, F. Del Prete, Vincenzo Montesarchio, Roberta Modica, M. Muto, Francesco Lassandro, M. Del Prete |
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| Přispěvatelé: | DEL PRETE, Michela, DI SARNO, Antonella, Modica, Roberta, Lassandro, F, Giorgio, A, Bianco, A, Muto, M, Gasperi, M, Del Prete, F, Colao, Annamaria, Montesarchio, V, Faggiano, Antongiulio |
| Rok vydání: | 2017 |
| Předmět: |
Adult
Male Pathology medicine.medical_specialty Prognosi Endocrinology Diabetes and Metabolism Rectum Contrast Media ceus Neuroendocrine tumors 030218 nuclear medicine & medical imaging 03 medical and health sciences 0302 clinical medicine Endocrinology Neuroendocrine tumor medicine Tumor Grading Humans neuroendocrine tumors prediction of response prognosis somatostatin analogues Aged Retrospective Studies Ultrasonography business.industry Human Growth Hormone Ultrasound Liver Neoplasms Retrospective cohort study Middle Aged medicine.disease Prognosis Biological Therapy Pancreatic Neoplasms Neuroendocrine Tumors medicine.anatomical_structure Homogeneous 030220 oncology & carcinogenesis Lymphatic Metastasis Female Radiology Pancreas business Contrast-enhanced ultrasound Follow-Up Studies |
| Zdroj: | Journal of endocrinological investigation. 40(12) |
| ISSN: | 1720-8386 |
| Popis: | The incidence of neuroendocrine tumors (NETs) is progressively increasing. Most cases arise from the digestive system, where ileum, rectum and pancreas represent the commonest site of origin. Liver metastases are frequently detected at diagnosis or during the follow-up. Contrast-enhanced ultrasound (CEUS) is used in patients with pancreatic NETs (P-NETs) and liver metastases from P-NET but its role has not been standardized. The aim of this retrospective study was to investigate CEUS in patients with P-NETs and liver metastases from P-NET both as prognostic factor and predictor of response to therapy with somatostatin analogues (SSAs). CEUS was performed at the diagnosis of NET and 3, 6 and 12 months after the beginning of SSAs. CEUS pattern was compared with contrast-enhanced computed tomography (CT) pattern. There was a significant association between CEUS and CT pattern (X 2 = 79.0; p |
| Databáze: | OpenAIRE |
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