Serum levels of stanniocalcin-1 in Holstein heifers and cows
| Autor: | Brian G. Talbot, Pierre Lacasse, M.C. Loiselle, Céline Ster, G.F. Wagner, G. Tremblay, L. Delbecchi |
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| Rok vydání: | 2009 |
| Předmět: |
medicine.medical_specialty
Mammary gland Ice calving Biology Paracrine signalling Endocrinology Food Animals Pregnancy Internal medicine Lactation medicine Animals Progesterone Dairy cattle Glycoproteins Estradiol Age Factors medicine.disease medicine.anatomical_structure Regression Analysis Gestation Cattle Female Animal Science and Zoology Hormone |
| Zdroj: | Domestic Animal Endocrinology. 36:105-109 |
| ISSN: | 0739-7240 |
| DOI: | 10.1016/j.domaniend.2008.11.002 |
| Popis: | Stanniocalcin-1 is a hormone that possesses both paracrine and endocrine functions and has recently been identified in mammals. While paracrine functions have been determined for several organs, the role of circulating stanniocalcin-1 in cattle is still unclear but, observations in mice and cows suggest that stanniocalcin-1 plays a role in both gestation and lactation. The changes in serum stanniocalcin-1 content in different physiological states have never been evaluated in ruminants. We measured stanniocalcin-1 levels in sera from cattle ranging in age from post-weaned calves to 17-month-old heifers and in sera from cows during lactation and pregnancy. Our results indicate that the blood concentration of stanniocalcin-1 is increased by pregnancy, but not by lactation. The highest levels of stanniocalcin-1 were found in young calves and during the non-lactating period preceding calving. This suggests that stanniocalcin-1 is important for gestation and the preparation of the mammary gland for lactation. |
| Databáze: | OpenAIRE |
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