| Autor: |
Eric B Fauman, Stella Keppo, Nicola Cerioli, Rupesh Vyas, Mitja Kurki, Mark Daly, Mary Pat Reeve |
| Přispěvatelé: |
Pfizer, Department of Art and Media, University of Helsinki, Aalto-yliopisto, Aalto University |
| Jazyk: |
angličtina |
| Rok vydání: |
2023 |
| Předmět: |
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| Popis: |
MotivationBiobank scale genetic associations results over thousands of traits can be difficult to visualize and navigate.ResultsWe have created LAVAA, a visualization web-application to generate genetic volcano plots for simultaneously considering the P-value, effect size, case counts, trait class and fine-mapping posterior probability at a single-nucleotide polymorphism (SNP) across a range of traits from a large set of genome-wide association study. We find that user interaction with association results in LAVAA can enrich and enhance the biological interpretation of individual loci.Availability and implementationLAVAA is available as a stand-alone web service (https://geneviz.aalto.fi/LAVAA/) and will be available in future releases of the finngen.fi website starting with release 10 in late 2023. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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