Bioequivalence of subcutaneous calcium and sodium heparins
| Autor: | Kenneth M. Moser, Cecil Hougie, Linda Aronson, Frank Bender |
|---|---|
| Rok vydání: | 1980 |
| Předmět: |
Adult
Male Adolescent Sodium Injections Subcutaneous chemistry.chemical_element Bioequivalence Calcium Pharmacology Subcutaneous injection medicine Humans Pharmacology (medical) Blood coagulation test medicine.diagnostic_test Heparin Age Factors Middle Aged Clotting time chemistry Therapeutic Equivalency Blood Coagulation Tests circulatory and respiratory physiology medicine.drug Partial thromboplastin time |
| Zdroj: | Clinical pharmacology and therapeutics. 27(2) |
| ISSN: | 0009-9236 |
| Popis: | The bioequivalence of subcutaneous porcine calcium and sodium heparins was studied in 48 normal male subjects randomly assigned to 1 of 4 study groups. Each subject received a single subcutaneous injection of 15,000 U of calcium heparin or 1 of 3 sodium heparins. Serial coagulation studies (Lee-White clotting time, activated partial thromboplastin time, thrombin calcium clotting time, and heparin level) were performed over 10 hr. There were no significant differences in anticoagulant effect between groups. |
| Databáze: | OpenAIRE |
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